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Friday, June 15, 2018

Obstetric Analgesia and Anesthesia Dr. Rayan G. Albarakati, MBBS ...
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Post-dural-puncture headache (PDPH) is a complication of puncture of the dura mater (one of the membranes that surround the brain and spinal cord). The headache is severe and described as "searing and spreading like hot metal," involving the back and front of the head, and spreading to the neck and shoulders, sometimes involving neck stiffness. It is exacerbated by movement, and sitting or standing, and relieved to some degree by lying down. Nausea, vomiting, pain in arms and legs, hearing loss, tinnitus, vertigo, dizziness and paraesthesia of the scalp are common.

It is a common side-effect of spinal anesthesia and lumbar puncture and may occasionally accidentally occur in epidural anesthesia. Leakage of cerebrospinal fluid through the dura mater puncture causes reduced fluid levels in the brain and spinal cord, and may lead to the development of PDPH hours or days later. Onset occurs within two days in 66 percent and within three days in ninety percent of PDPH cases. It occurs so rarely immediately after puncture that other possible causes should be investigated when it does.


Video Post-dural-puncture headache



Signs and symptoms

PDPH typically occurs hours to days after puncture and presents with symptoms such as headache (which is mostly bi-frontal or occipital) and nausea that typically worsen when the patient assumes an upright posture.


Maps Post-dural-puncture headache



Cause

The rate of PDPH is higher with younger patients, complicated or repeated puncture, and use of large diameter needles, in females, in pregnancy, and with darker skin. Modern, atraumatic needles such as the Sprotte or Whitacre spinal needle leave a smaller perforation and reduce the risk for PDPH.


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Pathophysiology

It is thought to result from a loss of cerebrospinal fluid into the epidural space. A decreased hydrostatic pressure in the subarachnoid space then leads to traction to the meninges with associated symptoms.


Medical vocabulary: What does Post-Dural Puncture Headache mean ...
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Prevention

The conventional medical wisdom over the last several decades for avoiding PDPH has been to use smaller gauge or modern needles which traumatize the dura less or make a smaller dura puncture, thereby lessening CSF leakage that causes PDPH. While these approaches have been effective at lowering PDPH rates, they have been unsuccessful at completely preventing PDPH. There is evidence that a more effective preventative approach is to make a self-closing puncture in the dura, using a simple beveled needle with a specific angle and bevel orientation. This approach can also prevent PDPH headaches caused by over-penetration during epidural anesthesia (where dural puncture was never intended), since withdrawal of the needle allows the dural puncture to self-close.

The use of a 3-bevel (Quinke) needles is highly associated with PDPH as the geometry of the needle can create a "flap" that allows CSF leakage when inserted in standard horizontal position (open face of needle cephalad). Inserting the needle vertically (open face directed left or right) splits the dural fibers and reduced the flap size. However older clinicians advocate completely inverting the needle and inserting horizontally but upside down so the open face of the Quinke is directed caudad. This also creates a flap but the geometry is inverted so that the flap is on the inside of the dura and is forced closed by hydrostatic pressure. The incidence of PDPD using a Quinke needle in standard orientation is approximately 3%-7%, Approximately 1.5%-3% when inserted vertically; Approximately 0.1% when inserted inverted.

Evidence does not support the use of bed rest or intravenous fluids to prevent PDPH.


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Treatment

Some people require no other treatment than pain medications and bed rest. A 2015 review found tentative evidence to support the use of caffeine.

Persistent and severe PDPH may require an epidural blood patch. A small amount of the person's blood is injected into the epidural space near the site of the original puncture; the resulting blood clot then "patches" the meningeal leak. The procedure carries the typical risks of any epidural puncture. However, it is effective, and further intervention is rarely necessary.

However, very short-term use of IV hydrocortisone was found effective in reducing headache following spinal anesthesia. But, its clear mechanism of action is yet to be determined. Large-scale studies are recommended to consider the steroid therapy as a standard treatment for postdural puncture headache.


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References

Source of article : Wikipedia